FITC标记的磷酸化G蛋白信号转导调节因子19抗体
产品名称： FITC标记的磷酸化G蛋白信号转导调节因子19抗体
英文名称： Anti-phospho-RGS19(Ser24)/FITC
产品编号： HZ-5687R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-phospho-RGS19(Ser24)/FITC Conjugated antibody
FITC标记的磷酸化G蛋白信号转导调节因子19抗体
| 英文名称 | Anti-phospho-RGS19(Ser24)/FITC |
| 中文名称 | FITC标记的磷酸化G蛋白信号转导调节因子19抗体 |
| 别 名 | RGS19(phospho S24); RGS19(phospho Ser24); G alpha interacting protein; GAIP; GNAI3IP; Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G protein signalling 19; RGSGAIP; RGS19_HUMAN; Regulator of G-protein signaling 19; RGS19; G-alpha-interacting protein. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 肿瘤 免疫学 信号转导 细胞凋亡 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 25kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human RGS19 around the phosphorylation site of Ser24 [M(p-S)SH] |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase activating protein that functions to down regulate Galpha i/Galpha q linked signaling. Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. Subunit: Interacts with GIPC PDZ domain. Subcellular Location: Membrane; Lipid-anchor. Tissue Specificity: Highest expression in lung. Placenta, liver and heart also express high levels of GAIP. Post-translational modifications: Fatty acylated. Heavily palmitoylated in the cysteine string motif. Phosphorylated, mainly on serine residues. Similarity: Contains 1 RGS domain. Database links: UniProtKB/Swiss-Prot: P49795.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
G蛋白介导了许多细胞过程。该基因编码的蛋白属于G蛋白信号调节子家族（RGS），并与G蛋白GAI3特异性相互作用。这种蛋白是鸟苷三磷酸酶激活蛋白，其作用是下调GalPHA I／GalPHA Q连接信号。