CAPN10 MaxPab mouse polyclonal antibody (B01)
产品名称： CAPN10 MaxPab mouse polyclonal antibody (B01)
英文名称： CAPN10 MaxPab mouse polyclonal antibody (B01)
产品编号： H00011132-B01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human CAPN10 protein.
- Immunogen:
- CAPN10 (NP_075571.1, 1 a.a. ~ 672 a.a) full-length human protein.
- Sequence:
- MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSGFPSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAYDREVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLSAIRAVAKNTTPGAALPAGEWGTVQLRGSWRVGQTAGGSRNFASYPTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTEFHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTIATRIDRPSIHSQEMLGQFLQEVSVMAVMKT
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of CAPN10 expression in transfected 293T cell line (H00011132-T01) by CAPN10 MaxPab polyclonal antibody.
Lane 1: CAPN10 transfected lysate(73.92 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 11132
- GeneBank Accession#:
- NM_023083.2
- Protein Accession#:
- NP_075571.1
- Gene Name:
- CAPN10
- Gene Alias:
- -
- Gene Description:
- calpain 10
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000164509,calcium-activated neutral protease
- Related Disease
- Adrenal Hyperplasia, Congenital
- Adrenal hyperplasia, congenital
- Alzheimer Disease
- Alzheimer disease
- Amenorrhea
- Arteriosclerosis
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Calcinosis
- Cardiovascular Diseases
- Colorectal Neoplasms
- Coronary Artery Disease
- Coronary Disease
- Cystic Fibrosis
- Cystic fibrosis
- Diabetes Complications
- Diabetes Mellitus
- Diabetes Mellitus, Type 2