POLG2 MaxPab rabbit polyclonal antibody (D01)
产品名称： POLG2 MaxPab rabbit polyclonal antibody (D01)
英文名称： POLG2 MaxPab rabbit polyclonal antibody (D01)
产品编号： H00011232-D01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human POLG2 protein.
- Immunogen:
- POLG2 (AAH09194.1, 1 a.a. ~ 485 a.a) full-length human protein.
- Sequence:
- MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPAYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of POLG2 expression in transfected 293T cell line (H00011232-T02) by POLG2 MaxPab polyclonal antibody.
Lane 1: POLG2 transfected lysate(54.90 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunoprecipitation
- Immunoprecipitation of POLG2 transfected lysate using anti-POLG2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with POLG2 purified MaxPab mouse polyclonal antibody (B01P) (H00011232-B01P).
- Protocol Download
- Entrez GeneID:
- 11232
- GeneBank Accession#:
- BC009194
- Protein Accession#:
- AAH09194.1
- Gene Name:
- POLG2
- Gene Alias:
- HP55,MTPOLB,PEOA4,POLB,POLG-BETA,POLGB
- Gene Description:
- polymerase (DNA directed), gamma 2, accessory subunit
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions
- Other Designations:
- mitochondrial DNA polymerase, accessory subunit
- Gene Pathway
- Related Disease
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Hepatitis C, Chronic
- Liver Cirrhosis
- Lung carcinoma, small cell
- Lung Neoplasms
- Ophthalmoplegia, Chronic Progressive External