SIRPA (Human) Recombinant Protein
产品名称： SIRPA (Human) Recombinant Protein
英文名称： SIRPA (Human) Recombinant Protein
产品编号： H00140885-G01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Human SIRPA full-length ORF (AAH33092.1) recombinant protein without tag.
- Sequence:
- MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVLVAAGETATLRCTATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNTAAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREITQVQSLDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKPEPSFSEYASVQVPRK
- Theoretical MW (kDa):
- 55.4
- Form:
- Liquid
- Preparation Method:
- in vitro wheat germ expression system with proprietary liposome technology
- Storage Buffer:
- 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Note:
- Best use within three months from the date of receipt of this protein.
- Publication Reference
- 1.
- Production and partial purification of membrane proteins using a liposome-supplemented wheat cell-free translation system.
Nozawa A, Ogasawara T, Matsunaga S, Iwasaki T, Sawasaki T, Endo Y. BMC Biotechnol. 2011 Apr 11;11:35.
- Application Image
- Antibody Production
- Functional Study
- Compound Screening
- Entrez GeneID:
- 140885
- GeneBank Accession#:
- BC033092.1
- Protein Accession#:
- AAH33092.1
- Gene Name:
- SIRPA
- Gene Alias:
- BIT,CD172A,MFR,MYD-1,P84,PTPNS1,SHPS-1,SHPS1,SIRP,SIRP-ALPHA-1,SIRPalpha,SIRPalpha2
- Gene Description:
- signal-regulatory protein alpha
- Omim ID:
- 602461
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000030001,SHP substrate-1,brain-immunoglobulin-like molecule with tyrosine-based activation motifs,macrophage fusion receptor,myd-1 antigen,protein tyrosine phosphatase, non-receptor type substrate 1,signal regulatory protein, alpha type 1,signal