FITC标记的蛋白酶体PSMα4/20S Proteasome α4抗体
产品名称： FITC标记的蛋白酶体PSMα4/20S Proteasome α4抗体
英文名称： Anti-PSMA4/FITC
产品编号： HZ-12260R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PSMA4/FITC Conjugated antibody
FITC标记的蛋白酶体PSMα4/20S Proteasome α4抗体
| 英文名称 | Anti-PSMA4/FITC |
| 中文名称 | FITC标记的蛋白酶体PSMα4/20S Proteasome α4抗体 |
| 别 名 | HC9; HsT17706; Macropain subunit C9; MGC111191; MGC12467; MGC24813; Multicatalytic endopeptidase complex subunit C9; Proteasome (prosome macropain) subunit alpha type 4; Proteasome alpha 4 subunit; Proteasome component C9; Proteasome subunit alpha type 4; Proteasome subunit alpha type-4; Proteasome subunit HC9; Proteasome subunit L; PSA4_HUMAN; PSC9; PSMA 4; psmA4. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Horse, Monkey, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 29kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human PSMA4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: The proteasome represents a large protein complex that exists inside all eukaryotes and archaea, and in some bacteria. The main function of proteasomes is to degrade unnecessary or damaged proteins by proteolysis. The most common form of the proteasome, known as the 26S Proteasome, contains one 20S Proteasome core particle structure and two 19S regulatory caps. The 20S Proteasome core is hollow and forms an enclosed cavity, where proteins are degraded, as well as openings at the two ends to allow the target protein to enter. The 20S Proteasome core particle contains many subunits, depending on the organism. All of the subunits fall into one of two types: alpha subunits, which are structural, serve as docking domains for the regulatory particles and exterior gates blocking unregulated access to the interior cavity; or beta subunits, which are predominantly catalytic. The outer two rings in the proteasome consist of seven ?subunits each, and the inner two rings each consist of seven beta subunits. Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Subcellular Location: Cytoplasm. Nucleus. Similarity: Belongs to the peptidase T1A family. Database links: Entrez Gene: 5685 Human Entrez Gene: 26441 Mouse Entrez Gene: 29671 Rat Omim: 176846 Human SwissProt: P25789 Human SwissProt: Q9R1P0 Mouse SwissProt: P21670 Rat Unigene: 251531 Human Unigene: 30270 Mouse Unigene: 440582 Mouse Unigene: 11076 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
蛋白酶体是一种存在于所有真核生物和古细菌以及某些细菌中的大蛋白复合物。蛋白酶体的主要功能是通过蛋白水解降解不必要的或受损的蛋白质。蛋白酶体最常见的形式，称为26S蛋白酶体，包含一个20S蛋白酶体核心颗粒结构和两个19S调节帽。20S蛋白酶体核心是中空的，形成一个封闭的空腔，在那里蛋白质降解，以及两端的开口，以允许目标蛋白质进入。20S蛋白酶体核心颗粒含有许多亚基，这取决于生物体。所有的亚基都属于两种类型之一：α亚基，是结构性的，用作调节粒子和外门对接区域，阻止不受调节地进入内腔；或β亚基，它们主要是催化性的。蛋白酶体的外两个环由七个组成？每个亚基和内两个环每个由七个β亚基组成。