GP1BA monoclonal antibody (M03), clone 2E5
产品名称： GP1BA monoclonal antibody (M03), clone 2E5
英文名称： GP1BA monoclonal antibody (M03), clone 2E5
产品编号： H00002811-M03
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant GP1BA.
- Immunogen:
- GP1BA (AAH27955, 19 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- ICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVPFNRL
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Applications
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged GP1BA is 3 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 2811
- GeneBank Accession#:
- BC027955
- Protein Accession#:
- AAH27955
- Gene Name:
- GP1BA
- Gene Alias:
- BSS,CD42B,CD42b-alpha,GP1B,MGC34595
- Gene Description:
- glycoprotein Ib (platelet), alpha polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq
- Other Designations:
- platelet glycoprotein Ib alpha polypeptide,platelet membrane glycoprotein 1b-alpha subunit
- Interactome
- Gene Pathway
- Related Disease
- Acute Chest Syndrome
- Acute Disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Aneurysm, Ruptured
- Angina, Unstable
- Antiphospholipid Syndrome
- Arterial Occlusive Diseases
- Arteriosclerosis
- Atherosclerosis
- Atherosclerosis
- Bernard-Soulier Syndrome
- Blood Platelet Disorders
- Brain Ischemia
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Carotid Artery Diseases
- Carotid Stenosis
- Cerebral Hemorrhage