PICK1 Rabbit pAb (APR21745N)-抗体-抗体-生物在线
安诺伦(北京)生物科技有限公司
PICK1 Rabbit pAb (APR21745N)

PICK1 Rabbit pAb (APR21745N)

商家询价

产品名称: PICK1 Rabbit pAb (APR21745N)

英文名称: PICK1 Rabbit pAb (APR21745N)

产品编号: APR21745N

产品价格: null

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围:

安诺伦(北京)生物科技有限公司
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分子量:Calculated MW: 39kDa/46kDa
Observed MW: 53kDa

细胞定位:Cell junction, Cytoplasm, Lipid-anchor, Membrane, Peripheral membrane protein, cytoskeleton, perinuclear region, postsynaptic cell membrane, postsynaptic density, synapse, synaptosome

稀释方法:WB 1:500 - 1:2000

总结:The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.